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Ron N Apte Selected Research

Therapeutics

4/2022Pathogenetic role and clinical significance of interleukin-1β in cancer.
11/2019Proinflammatory Macrophages Promote Multiple Myeloma Resistance to Bortezomib Therapy.
1/2017Targeting the Tumor Microenvironment by Intervention in Interleukin-1 Biology.
6/2015Blocking IL1β Pathway Following Paclitaxel Chemotherapy Slightly Inhibits Primary Tumor Growth but Promotes Spontaneous Metastasis.
12/2014Classification of current anticancer immunotherapies.
12/2014Modification of topoisomerases in mammospheres derived from breast cancer cell line: clinical implications for combined treatments with tyrosine kinase inhibitors.
2/2014Critical role for IL-1β in DNA damage-induced mucositis.
1/2014The role IL-1 in tumor-mediated angiogenesis.
1/2011Targeting of polymeric nanoparticles to lung metastases by surface-attachment of YIGSR peptide from laminin.
3/2010Effects of IL-1 molecules on growth patterns of 3-MCA-induced cell lines: an interplay between immunogenicity and invasive potential.
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Ron N Apte Research Topics

Disease

39Neoplasms (Cancer)
04/2022 - 08/2002
29Inflammation (Inflammations)
05/2018 - 08/2002
8Neoplasm Metastasis (Metastasis)
11/2015 - 03/2003
8Fibrosarcoma
11/2010 - 01/2003
6Carcinogenesis
12/2015 - 04/2006
5Experimental Melanoma
01/2021 - 03/2003
4Colitis
01/2021 - 04/2014
4Rheumatoid Arthritis
01/2021 - 03/2003
4Hypoxia (Hypoxemia)
12/2013 - 10/2009
3Melanoma (Melanoma, Malignant)
01/2021 - 03/2003
3Necrosis
10/2015 - 02/2010
3Atherosclerosis
06/2012 - 11/2007
2Weight Loss (Weight Reduction)
05/2018 - 02/2017
2Encephalitis (Encephalitis, Rasmussen)
01/2018 - 01/2016
2Fatty Liver
05/2014 - 11/2011
1Multiple Myeloma
11/2019
1Tics (Tic)
11/2019
1Mesothelioma
01/2018
1Alzheimer Disease (Alzheimer's Disease)
01/2018
1Hypertension (High Blood Pressure)
01/2018
1Fatigue
02/2017
1Colorectal Neoplasms (Colorectal Cancer)
02/2017
1Wounds and Injuries (Trauma)
01/2017
1Colonic Neoplasms (Colon Cancer)
12/2015
1Lewis Lung Carcinoma
11/2015
1Breast Neoplasms (Breast Cancer)
12/2014
1Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
06/2014
1Alcoholic Fatty Liver
05/2014
1Mucositis
02/2014
1Residual Neoplasm
01/2013
1Obesity
01/2013

Drug/Important Bio-Agent (IBA)

27Interleukin-1 (Interleukin 1)IBA
01/2018 - 08/2002
26CytokinesIBA
01/2019 - 08/2002
8Interleukin-1 Receptors (Interleukin 1 Receptor)IBA
06/2015 - 03/2003
7Interleukin-1alpha (Interleukin 1 alpha)IBA
01/2012 - 01/2003
6Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link
01/2017 - 01/2004
6Proteins (Proteins, Gene)FDA Link
12/2014 - 08/2002
5AlarminsIBA
01/2018 - 01/2012
5matrigelIBA
04/2013 - 03/2003
3InterleukinsIBA
05/2018 - 05/2014
3Dextrans (Dextran)FDA Link
05/2018 - 04/2014
3sodium sulfate (sodium bisulfate)FDA LinkGeneric
05/2018 - 04/2014
3CarcinogensIBA
06/2016 - 02/2007
3Pharmaceutical PreparationsIBA
11/2015 - 01/2011
3Interleukin-1beta (Interleukin 1 beta)IBA
07/2008 - 03/2003
2Interleukin-12 (IL 12)IBA
01/2019 - 03/2010
2A-Form DNA (A-DNA)IBA
01/2016 - 10/2015
2InflammasomesIBA
12/2015 - 01/2013
2AntibodiesIBA
04/2014 - 04/2010
2Apolipoproteins E (ApoE)IBA
06/2012 - 02/2011
2LigandsIBA
11/2010 - 04/2009
2MethylcholanthreneIBA
12/2009 - 02/2007
1aldesleukin (Proleukin)FDA Link
01/2021
1Bortezomib (Velcade)FDA Link
11/2019
1Proteasome InhibitorsIBA
11/2019
1Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA
01/2019
1Interleukin-10 (Interleukin 10)IBA
01/2019
1Granzymes (Granzyme)IBA
01/2019
116S Ribosomal RNAIBA
05/2018
1Carbon Nanotubes (Carbon Nanotube)IBA
01/2018
1Crocidolite Asbestos (Blue Asbestos)IBA
01/2018
1Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA
01/2018
1candesartanIBA
01/2018
1Captopril (Capoten)FDA LinkGeneric
01/2018
1LipopolysaccharidesIBA
01/2018
1Hormones (Hormone)IBA
01/2018
1Oxaliplatin (Eloxatin)FDA LinkGeneric
02/2017
1Aspartate Aminotransferases (Aspartate Transaminase)IBA
02/2017
1Alkaline PhosphataseIBA
02/2017
1Irinotecan (Camptosar)FDA LinkGeneric
02/2017
1Interleukin-16 (Interleukin 16)IBA
01/2017
1Interleukin-33IBA
01/2017
1Neurotransmitter Agents (Neurotransmitter)IBA
01/2016
1Angiotensin IIIBA
01/2016
1Type 1 Angiotensin ReceptorIBA
01/2016
1E-SelectinIBA
11/2015
1PolymersIBA
11/2015
1Fluorescein-5-isothiocyanate (FITC)IBA
11/2015
1Paclitaxel (Taxol)FDA LinkGeneric
06/2015
1AntigensIBA
12/2014
1Monoclonal AntibodiesIBA
12/2014
1Erlotinib Hydrochloride (CP 358,774)FDA Link
12/2014
1Gefitinib (Iressa)FDA Link
12/2014
1Tyrosine Kinase InhibitorsIBA
12/2014
1Biological ProductsIBA
12/2014
12- cyclohexylidenhydrazo- 4- phenyl- thiazoleIBA
12/2014
1EnzymesIBA
12/2014
1Etoposide (VP 16)FDA LinkGeneric
12/2014
1ammonium trichloro(dioxoethylene-O,O'-)tellurate (AS 101)IBA
06/2014
1Immunologic Factors (Immunomodulators)IBA
06/2014
1TelluriumIBA
06/2014
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
04/2013
1Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
04/2013
1Oxygen (Dioxygen)IBA
01/2012

Therapy/Procedure

12Therapeutics
04/2022 - 04/2006
5Immunotherapy
12/2014 - 01/2003
2Microspheres (Microsphere)
11/2007 - 01/2003
1Intravenous Injections
11/2015
1Drug Therapy (Chemotherapy)
06/2015
1Bone Marrow Transplantation (Transplantation, Bone Marrow)
04/2014